Below you will find recent publications from the berkhoutlab.
|
|
IN PRESS |
|
| |
|
| 2006 |
|
| |
Berkhout B, Haasnoot J. The interplay between virus infection and the cellular RNA interference machinery. FEBS Lett. 2006 Mar 6; [Epub ahead of print] |
| |
|
| 2005 |
|
| |
Berkhout B. It's the virus, stupid - part 2. Retrovirology. 2005 Dec 16;2(1):78 [Epub ahead of print] |
| |
Benschop KS, Schinkel J, Minnaar RP, Pajkrt D, Spanjerberg L, Kraakman HC, Berkhout B, Zaaijer HL, Beld MG, Wolthers KC. Human parechovirus infections in Dutch children and the association between serotype and disease severity. Clin Infect Dis. 2006 Jan 15;42(2):204-10. Epub 2005 Dec 12. |
| |
Berkhout B. RNAi Europe 2005. IDrugs. 2005 Dec;8(12):978-81. |
| |
Naarding MA, Ludwig IS, Groot F, Berkhout B, Geijtenbeek TB, Pollakis G, Paxton WA. Lewis X component in human milk binds DC-SIGN and inhibits HIV-1 transfer to CD4 T lymphocytes. J Clin Invest. 2005 Nov 1;115(11):3256-3264. Epub 2005 Oct 20. |
| |
Nethe M, Berkhout B, van der Kuyl AC. Retroviral superinfection resistance. Retrovirology. 2005 Aug 18;2:52. |
| |
van der Hoek L , Sure K , Ihorst G , Stang A , Pyrc K , Jebbink MF , Petersen G , Forster J , Berkhout B , Uberla K. Croup Is Associated with the Novel Coronavirus NL63. PLoS Med. 2005 Aug;2(8):e240. Epub 2005 Aug 23. |
| |
Abbink TE , Ooms M , Haasnoot PC , Berkhout B. The HIV-1 leader RNA conformational switch regulates RNA dimerization but does not regulate mRNA translation. Biochemistry. 2005 Jun 28;44(25):9058-66. |
| |
van der Hoek L , Berkhout B.
Questions concerning the New Haven coronavirus. J Infect Dis. 2005 Jul 15;192(2):350-1; author reply 353-4. |
| |
van Opijnen T , Berkhout B . The host environment drives HIV-1 fitness. Rev Med Virol. 2005 Jul-Aug;15(4):219-33. |
| |
Berkhout B. Retroviral nucleocapsid--third international symposium. IDrugs. 2001 Nov;4(11):1250-1. |
| |
Jeeninga RE , Jan B , van der Linden B , van den Berg H , Berkhout B.
Construction of a minimal HIV-1 variant that selectively replicates in leukemic derived T-cell lines: towards a new virotherapy approach. Cancer Res. 2005 Apr 15;65(8):3347-55. |
| |
Markusic D, Oude-Elferink R, Das AT, Berkhout B, Seppen J. Comparison of single regulated lentiviral vectors with rtTA expression driven by an autoregulatory loop or a constitutive promoter. Nucleic Acids Res. 2005 Apr 4;33(6):e63. |
| |
Berkhout B, de Ronde A, van der Hoek L. Aggressive HIV-1? Retrovirology. 2005 Feb 28;2(1):13 [Epub ahead of print] |
| |
Das AT, Baldwin CE, Vink M, Berkhout B.
Improving the Safety of a Conditional-Live Human Immunodeficiency Virus Type 1 Vaccine by Controlling both Gene Expression and Cell Entry. J Virol. 2005 Mar;79(6):3855-8. |
| |
van der Hoek L, Back N, Jebbink MF, de Ronde A, Bakker M, Jurriaans S, Reiss P, Parkin N, Berkhout B. Increased multinucleoside drug resistance and decreased replicative capacity of a human immunodeficiency virus type 1 variant with an 8-amino-Acid insert in the reverse transcriptase. J Virol. 2005 Mar;79(6):3536-43. |
| |
Das AT, Vink M, Berkhout B. Alternative tRNA Priming of Human Immunodeficiency Virus Type 1 Reverse Transcription Explains Sequence Variation in the Primer-Binding Site That Has Been Attributed to APOBEC3G Activity. J Virol. 2005 Mar;79(5):3179-81. |
| |
Groot F, Geijtenbeek TB, Sanders RW, Baldwin CE, Sanchez-Hernandez M, Floris R, van Kooyk Y, de Jong EC, Berkhout B. Lactoferrin Prevents Dendritic Cell-Mediated Human Immunodeficiency Virus Type 1 Transmission by Blocking the DC-SIGN--gp120 Interaction. J Virol. 2005 Mar;79(5):3009-15. |
| |
Westerhout EM, Ooms M, Vink M, Das AT, Berkhout B. HIV-1 can escape from RNA interference by evolving an alternative structure in its RNA genome. Nucleic Acids Res. 2005 Feb 01;33(2):796-804. |
| |
Moes E, Vijgen L, Keyaerts E, Zlateva K, Li S, Maes P, Pyrc K, Berkhout B, van der Hoek L, Van Ranst M. A novel pancoronavirus RT-PCR assay: frequent detection of human coronavirus NL63 in children hospitalized with respiratory tract infections in Belgium. BMC Infect Dis. 2005 Feb 1;5(1):6 [Epub ahead of print] |
| 2004 |
|
| |
Pyrc K, Jebbink MF, Berkhout B, van der Hoek L. Genome structure and transcriptional regulation of human coronavirus NL63. Virol J. 2004 Nov 17;1(1):7 [Epub ahead of print] |
| |
van der Kuyl AC, van den Burg R, Hoyer MJ, Gruters RA, Osterhaus AD, Berkhout B. SIVdrl detection in captive mandrills: are mandrills infected with a third strain of simian immunodeficiency virus? Retrovirology. 2004 Nov 1;1(1):36 [Epub ahead of print] |
| |
Baldwin CE, Sanders RW, Deng Y, Jurriaans S, Lange JM, Lu M, Berkhout B. Emergence of a Drug-Dependent Human Immunodeficiency Virus Type 1 Variant during Therapy with the T20 Fusion Inhibitor. J Virol. 2004 Nov;78(22):12428-37. |
| |
Lemieux AM, Pare ME, Audet B, Legault E, Lefort S, Boucher N, Landry S, van Opijnen T, Berkhout B, Naghavi MH, Tremblay MJ, Barbeau B. T cell activation leads to poor activation of HIV-1 clade E LTR and weak association of NF-kappa B and NFAT to its enhancer region. J Biol Chem. 2004 Oct 1 [Epub ahead of print] |
| |
Kiselyeva Y, Ito Y, Lima RG, Grivel JC, Das AT, Berkhout B, Margolis LB.
Depletion of CD4 T lymphocytes in human lymphoid tissue infected ex vivo with doxycycline-dependent HIV-1. Virology. 2004 Oct 15;328(1):1-6. |
| |
Ooms M, Huthoff H, Russell R, Liang C, Berkhout B.
A riboswitch regulates RNA dimerization and packaging in human immunodeficiency virus type 1 virions. J Virol. 2004 Oct;78(19):10814-9. |
| |
Abbink T, Beerens N, Berkhout B.
Forced selection of a human immunodeficiency virus type 1 variant that uses a non-self tRNA primer for reverse transcription: involvement of viral RNA sequences and the reverse transcriptase enzyme. J Virol. 2004 Oct;78(19):10706-14. |
| |
Berkhout B, De Ronde A. APOBEC3G
versus reverse transcriptase in the generation of HIV-1 drug-resistance
mutations. AIDS.
2004 Sep 3;18(13):1861-3. |
| |
Sanders RW, Busser E, Moore JP, Lu M, Berkhout
B. Evolutionary repair of HIV type 1 gp41 with a kink
in the N-terminal helix leads to restoration of the six-helix
bundle structure. AIDS
Res Hum Retroviruses. 2004 Jul;20(7):742-9. |
| |
Das AT, Verhoef K, Berkhout B. A
Conditionally Replicating Virus as a Novel Approach Toward
an HIV Vaccine. Methods
Enzymol. 2004;388:359-79. |
| |
Bezemer D, Jurriaans S, Prins M, Van Der
Hoek L, Prins JM, De Wolf F, Berkhout B, Coutinho R, Back
NK. Declining trend in transmission of drug-resistant
HIV-1 in Amsterdam. AIDS.
2004 Jul 23;18(11):1571-1577. |
| |
Berkhout B, Floris R, Recio I, Visser S.
The antiviral activity of the milk protein lactoferrin
against the human immunodeficiency virus type 1.
Biometals. 2004 Jun;17(3):291-4. |
| |
Das AT, Verhoef K, Berkhout B. A
Conditionally Replicating Virus as a Novel Approach Toward
an HIV Vaccine. Methods
Enzymol. 2004;388:359-79. |
| |
Bezemer D, Jurriaans S, Prins M, Van Der
Hoek L, Prins JM, De Wolf F, Berkhout B, Coutinho R, Back
NK. Declining trend in transmission of drug-resistant
HIV-1 in Amsterdam. AIDS.
2004 Jul 23;18(11):1571-1577. |
| |
Berkhout B, Floris R, Recio I, Visser S.
The antiviral activity of the milk protein lactoferrin
against the human immunodeficiency virus type 1.
Biometals.
2004 Jun;17(3):291-4. |
| |
Berkhout B. RNA interference as an
antiviral approach: targeting HIV-1. Curr
Opin Mol Ther. 2004 Apr;6(2):141-5. |
| |
Van Opijnen T, Kamoschinski J, Jeeninga RE,
Berkhout B. The Human Immunodeficiency
Virus Type 1 Promoter Contains a CATA Box Instead of a TATA
Box for Optimal Transcription and Replication.
J
Virol. 2004 Jul;78(13):6883-90. |
| |
Huthoff H, Das AT, Vink M, Klaver B, Zorgdrager F, Cornelissen M, Berkhout B. A human \immunodeficiency virus type 1-infected individual with low viral load harbors a virus variant that exhibits an in vitro RNA dimerization defect. J Virol. 2004 May;78(9):4907-13. |
| |
Sanders RW, Dankers MM, Busser E, Caffrey
M, Moore JP, Berkhout B. Evolution
of the HIV-1 envelope glycoproteins with a disulfide bond
between gp120 and gp41. Retrovirology.
2004 Mar 9;1(1):3. |
| |
Kostense S, Koudstaal W, Sprangers M, Weverling
GJ, Penders G, Helmus N, Vogels R, Bakker M, Berkhout B, Havenga
M, Goudsmit J. Adenovirus types
5 and 35 seroprevalence in AIDS risk groups supports type
35 as a vaccine vector. AIDS.
2004 May 21;18(8):1213-1216. |
| |
Huthoff H, Das AT, Vink M, Klaver B, Zorgdrager
F, Cornelissen M, Berkhout B. A human immunodeficiency
virus type 1-infected individual with low viral load harbors
a virus variant that exhibits an in vitro RNA dimerization
defect. J
Virol. 2004 May;78(9):4907-13. |
| |
van der Hoek L, Pyrc K, Jebbink MF, Vermeulen-Oost
W, Berkhout RJ, Wolthers KC, Wertheim-van Dillen PM, Kaandorp
J, Spaargaren J, Berkhout B. Identification
of a new human coronavirus. Nat
Med. 2004 Apr;10(4):368-73. Epub 2004 Mar 21. |
| |
van Opijnen T, Jeeninga RE, Boerlijst MC,
Pollakis GP, Zetterberg V, Salminen M, Berkhout B.
Human immunodeficiency virus type 1 subtypes
have a distinct long terminal repeat that determines the replication
rate in a host-cell-specific manner. J
Virol. 2004 Apr;78(7):3675-83. |
| |
Huthoff H, Girard F, Wijmenga SS, Berkhout
B. Evidence for a base triple in the free HIV-1 TAR
RNA. RNA.
2004 Mar;10(3):412-423. |
| |
Das AT, Brummelkamp TR, Westerhout EM, Vink
M, Madiredjo M, Bernards R, Berkhout B. Human immunodeficiency
virus type 1 escapes from RNA interference-mediated inhibition.
J
Virol. 2004 Mar;78(5):2601-5. |
| |
Marcel Ooms, Koen Verhoef, Edwin Southern,
Hendrik Huthoff and Ben Berkhout. Probing alternative
foldings of the HIV-1 leader RNA by antisense oligonucleotide
scanning arrays. Nucleic
Acids Research. 2004 Feb 3;32(2):819-27. |
| |
Das AT, Zhou X, Vink M, Klaver B, Verhoef
K, Marzio G, Berkhout B. Viral evolution as a tool
to improve the tetracycline-regulated gene expression system.
J
Biol Chem. 2004 Feb 2 [Epub ahead of print]. |
| 2003 |
|
| |
Joost Haasnoot PC, Cupac D,
Berkhout B. Inhibition of virus replication by RNA
interference. J
Biomed Sci. 2003;10(6 Pt 1):607-16. |
| |
Baldwin CE, Sanders RW and Berkhout
B. Inhibiting HIV-1 entry with fusion inhibitors.
Current
Medical Cemistry, 2003, Sep;10(17):1633-42. |
| |
Huthoff H, Bugala K, Barciszewski
J, Berkhout B. On the importance of the primer activation
signal for initiation of tRNA(lys3)-primed reverse transcription
of the HIV-1 RNA genome. Nucleic
Acids Res. 2003 Sep 1;31(17):5186-94. |
| |
Kulinski T, Olejniczak M, Huthoff
H, Bielecki L, Pachulska-Wieczorek K, Das AT, Berkhout B,
Adamiak RW. The apical loop of the HIV-1 TAR RNA hairpin
is stabilized by a cross-loop base pair. J
Biol Chem. 2003 Jul 25 [Epub ahead of print]. |
| |
Pereira CF, Paridaen JT, Rutten
K, Huigen MC, van de Bovenkamp M, Middel J, Beerens N, Berkhout
B, Schuurman R, Marnett LJ, Verhoef J, Nottet HS. Aspirin-like
molecules that inhibit human immunodeficiency virus 1 replication.
Antiviral
Res. 2003 May;58(3):253-63. |
| |
Berkhout B, Floris R, Visser
S, Recio I. Antibacterial effects of the milk protein
lactoferrin. AGROFood industry hi-tech 2003;may/june(14):32-33. |
| |
Berkhout B, Floris R, Recio
I, Visser S. Antiviral effects of the milk protein
lactoferrin. AGROFood industry hi-tech 2003;march/april:43-46. |
| |
Brasey A, Lopez-Lastra M, Ohlmann
T, Beerens N, Berkhout B, Darlix JL, Sonenberg N. The
leader of human immunodeficiency virus type 1 genomic RNA
harbors an internal ribosome entry segment that is active
during the G2/M phase of the cell cycle.
J Virol. 2003 Apr;77(7):3939-49. |
| |
Abbink TE, Berkhout B. A
novel long distance base-pairing interaction in human immunodeficiency
virus type 1 RNA occludes the Gag start codon. J
Biol Chem. 2003 Mar 28;278(13):11601-11. |
| |
Andersen ES, Jeeninga RE, Damgaard
CK, Berkhout B, Kjems J. Dimerization and template
switching in the 5' untranslated region between various subtypes
of human immunodeficiency virus type 1. J
Virol. 2003 Mar;77(5):3020-30. |
| |
Florisa R, Recio I, Berkhout
B, Visser S. Antibacterial and antiviral effects of
milk proteins and derivatives thereof. Curr
Pharm Des. 2003;9(16):1257-75. |
| 2002 |
|
| |
Berkhout B, Verhoef K, Marzio
G, Klaver B, Vink M, Zhou X, Das AT. Conditional virus
replication as an approach to a safe live attenuated human
immunodeficiency virus vaccine.
J Neurovirol. 2002 Dec;8 Suppl 2:134-7. |
| |
Das AT, Zhou X, Vink M, Klaver
B, Berkhout B. Conditional live virus as a novel approach
towards a safe live attenuated HIV vaccine. Expert
Rev Vaccines. 2002 Oct;1(3):293-301. |
| |
Dirac AM, Huthoff H, Kjems J,
Berkhout B. Requirements for RNA heterodimerization
of the human immunodeficiency virus type 1 (HIV-1) and HIV-2
genomes. J
Gen Virol. 2002 Oct;83(Pt 10):2533-42. |
| |
Sanders RW, Korber B, Lu M,
Berkhout B, Moore JP. Mutational analyses and natural
variability of the gp41 ectodomain. In: HIV Molecular
Immunology Database 2002; eds: Korber B, Brander C, Haynes
BF, Koup R, Kuiken C, Moore JP, Walker BD, Watkins DI; publ:
Theoretical Biology and Biophysics, Los Alamos National Laboratory,
Los
Alamos, 2002: I-23-47. |
| |
Sanders RW, Vesanen M, Schuelke
N, Master A, Schiffner L, Kalyanaraman R, Paluch M, Berkhout
B, Maddon PJ, Olson WC, Lu M, Moore JP. Stabilization
of the soluble, cleaved, trimeric form of the envelope glycoprotein
complex of human immunodeficiency virus type 1. J
Virol. 2002 Sep;76(17):8875-89. |
| |
Sanders RW, De Jong EC, Baldwin
CE, Schuitemaker J, Kapsenberg ML, Berkhout B (2002) Differential
transmission of human immunodeficiency virus type 1 by effector
dendritic cells.
J Virol. 2002 Aug;76(15):7812-21. |
| |
Huthoff H, Berkhout B. Multiple
secondary structure rearrangements during HIV-1 RNA dimerization.
Biochemistry.
2002 Aug 20;41(33):10439-45. |
| |
Berkhout B, van Wamel JL, Beljaars
L, Meijer DK, Visser S, Floris R. Characterization
of the anti-HIV effects of native lactoferrin and other milk
proteins and protein-derived peptides. Antiviral
Res. 2002 Aug;55(2):341-55. |
| |
Dirac AM, Huthoff H, Kjems J,
Berkhout B. Regulated HIV-2 RNA dimerization by means
of alternative RNA conformations. Nucleic
Acids Res. 2002 Jun 15;30(12):2647-55. |
| |
Berkhout B, Ooms M, Beerens
N, Huthoff H, Southern E, Verhoef K. In vitro evidence
that the untranslated leader of the HIV-1 genome as an RNA
checkpoint that regulates multiple functions through confirmational
changes.
J Biol Chem. 2002 May 31;277(22):19967-75. |
| |
Beerens N, and Berkhout. Swichting
the in vitro tRNA-usage of HIV-1 by simultaneous adaptation
of the PBS and PAS. RNA.
2002 Mar;8(3):357-69. |
| |
Beerens N, and Berkhout. The
tRNA primer activation signal in the Human Immunodeficiency
Virus type 1 genome is important for initiation and processive
elongation of reverse transcription. (2002)
J. Virol. 76, 2329-2339. |
| |
Marzio G, Vink M, Verhoef K,
de Ronde A and Berkhout B. Efficient HIV replication
requires a fine-tuned level of transcription. (2002)
J. Virol. 76, 3084-3088. |
| |
Berkhout B, Grigoriev A, Bakker
M and Lukashov VV. The codon and amino acid usage
in retroviral genomes is consistatent with a virus-specific
nucleotide pressure. (2002)
AIDS Res. Hum. Retrov. 18, 133-141. |
| |
Berkhout B, Marzio G and Verhoef
K.Control over HIV-1 replication by an antibiotic;
a novel vaccination strategy with a drug-dependent virus.
(2002)
Virus Research 82, 103-108. |
| |
Berkhout B, Marzio G, Verhoef
K. Control over HIV-1 replication by an antibiotic;
a novel vaccination strategy with a drug-dependent virus.
Virus
Res. 2002 Jan 30;82(1-2):103-8. |
| 2001 |
|
| |
Berkhout B, Vastenhouw N, Klasens
BI, Huthoff H. Structural features in
the HIV-1 repeat region facilitate strand-transfer during
reverse transcription. RNA
2001 Aug;7(8):1097-114 |
| |
Beerens N, Groot F and Berkhout
B. Initiation of HIV-1 reverse transcription is regulated
by a primer activation signal.
J Biol Chem. 2001 Aug 17;276(33):31247-56. |
|
Huthoff H and Berkhout B. Mutations
in the TAR hairpin affect the equilibrium between alternative
conformations of the HIV-1 leader RNA. Nucleic
Acid Research. 2001 Jun 15;29(12):2594-600. |
|
Dirac A, Huthoff, H and Berkhout
B; Identification of the primary dimerization signal
in HIV-2 RNA. J
Biol Chem 2001 Jun 7. |
|
Marzio G, Verhoef K, Vink
M, and Berkhout B. In vitro evolution of a highly
replicating, doxycycline-dependent HIV for application in
vaccine studies. Proc
Natl Acad Sci U S A. 2001 May 22;98(11):6342-7.
|
|
Jeeninga RE, Keulen W, Boucher C, Sanders
RW, Berkhout B. Evolution of azt resistance in hiv-1:
the 41-70 intermediate that is not observed in vivo has a
replication defect. Virology.
2001 May 10;283(2):294-305. |
|
Berkhout B, Das AT, Beerens N, Araya
A, and Litvak S. HIV-1 RNA Editing, Hypermutation,
and Error-Prone Reverse Transcription. Science
2001 April 6; 292: 7. |
|
Verhoef K, Bilodeau PS, van
Wamel JLB, Kjems J, Stoltzfus CM and Berkhout B. 2001. Repair
of a Rev-minus HIV-1 mutant by activation of a cryptic splice
site. J
Virol. 2001 Apr;75(7):3495-500. |
|
Huthoff H and Berkhout
B. 2001. Two alternating structures for the HIV-1
leader RNA. RNA.
2001 Jan;7(1):143-57. |
|
Verhoef K, Marzio G, Hillen
W, Bujard H and Berkhout B. 2001. Strict control
of HIV-1 replication by a genetic switch: Tet for Tat.
J Virol. 2001 Jan;75(2):979-87. |
| PREVIOUS |
Back,
N. K. T., M. Nijhuis, W. Keulen, C. A. B. Boucher, B. B. Oude
Essink, A. B. P. van Kuilenburg, A. H. Van Gennip, and B.
Berkhout. 1996. Reduced replication of 3TC-resistant HIV-1
variants in primary cells due to a processivity defect of
the reverse transcriptase enzyme. EMBO
Journal 15:4040-4049. |
|
Beerens
N, Klaver B, Berkhout B. 2000. A structured RNA motif plays
a role in the correct placement of the tRNAlys3 primer onto
the human immunodeficiency virus genome. Journal
of Virology 74, 2227-2238. |
|
Berkhout,
B., A. Gatignol, A. B. Rabson, and K. T. Jeang. 1990. TAR-independent
activation of the HIV-1 LTR: evidence that tat requires
specific regions of the promoter. Cell
62:757-767 |
|
Berkhout
B, Jebbink MF and Zsiros J. 1999. Identification of an active
reverse transcriptase encoded by a human endogenous HERV-K
retrovirus. Journal
of Virology 73, 2365-2375. |
|
Berkhout,
B., R. H. Silverman, and K. T. Jeang. 1989. Tat trans-activates
the human immunodeficiency virus through a nascent RNA target.
Cell
59:273-282. |
|
Berkhout
B and van Wamel JLB. 1996. Role of the DIS hairpin in replication
of human immunodeficiency virus type 1. Journal
of Virology 70, 6723-6732. |
|
Berkhout
B and van Wamel JLB. 2000. The leader of the HIV-1 RNA genome
forms a compactly folded tertiary structure. RNA
6, 282-295. |
|
Berkhout
B, Verhoef K, van Wamel JLB and Back N. 1999. Genetic instability
of live, attenuated human immunodeficiency virus vaccine strains.
Journal
of Virology 73, 1138-1145. |
|
Das
AT, Klaver B and Berkhout B. 1995. Reduced replication of
human immunodeficiency virus type 1 mutants that use reverse
transcription primers other than the natural tRNAlys,3. Journal
of Virology 69: 3090-3097. |
|
Das
AT, Klaver B and Berkhout B. 1998. The 5' and 3'TAR elements
of the human immunodeficiency virus exert effects at several
points in the virus life cycle. Journal
of Virology 72, 9217-9223. |
|
Das
AT, Klaver B and Berkhout B. 1999. A hairpin structure in
the R region of the human immunodeficiency virus type 1 RNA
genome is instrumental in polyadenylation site selection.
Journal
of Virology 73, 81-91. |
|
Das
AT, Klaver B, Klasens BIF, van Wamel JLB and Berkhout B. 1997.
A conserved hairpin motif in the R-U5 region of the human
immunodeficiency virus type 1 RNA genome is essential for
replication. Journal
of Virology 71, 2346-2356. |
|
Jeeninga
R, Hoogenkamp M, Armand-Ugon M, de Baar M, Verhoef K and Berkhout
B. 2000. Functional differences between the LTR transcriptional
promoters of HIV-1 subtypes A through G. Journal
of Virology 74, 3740-3751. |
|
Keulen
W, Back NAT, van Wijk A, Boucher CAB and Berkhout B. 1997.
Initial appearance of the 184 Ile variant in lamivudine-treated
patients is caused by the mutational bias of human immunodeficiency
virus type 1 Reverse Transcriptase. Journal
of Virology 71, 3346-3350. |
|
Klaver,
B. and B. Berkhout. 1994. Evolution of a disrupted TAR RNA
hairpin structure in the HIV-1 virus. EMBO
Journal 13:2650-2659. |
|
Verhoef
K and Berkhout B. 1999. A second-site mutation that restores
replication of a Tat-defective Human Immunodeficiency Virus.
Journal
of Virology 73, 2781-2789. |
|
Verhoef
K, Sanders RW, Fontaine V, Kitajima S, Berkhout B. 1999. Evolution
of the HIV-1 LTR promoter by conversion of an NF-kB enhancer
element into a GABP binding site. Journal
of Virology 73, 1331-1340. |
|
|
 |
